Search on: THROMBOXANE A2 
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Descriptor English:   Thromboxane A2 
Descriptor Spanish:   Tromboxano A2 
Descriptor Portuguese:   Tromboxano A2 
Synonyms English:   Rabbit Aorta Contracting Substance  
Tree Number:   D10.251.355.255.100.825.800
D23.469.050.175.800.800
Definition English:   An unstable intermediate between the prostaglandin endoperoxides and thromboxane B2. The compound has a bicyclic oxaneoxetane structure. It is a potent inducer of platelet aggregation and causes vasoconstriction. It is the principal component of rabbit aorta contracting substance (RCS). 
Indexing Annotation English:   /biosyn /physiol permitted
History Note English:   86(78); was see under THROMBOXANES 1978-85 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   14314 
Unique Identifier:   D013928 

Occurrence in VHL: 		 

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